Lets talk about what happens when Endocannabinoid System’s activated by cannabis these compounds bind to receptors. (specifically the cannabinoids, ie THC or CBD)
These receptors can be anywhere in your brain and body and any number of them can be activated.
& no they don’t function as
simply as THC + receptor = effect
In fact, when each one is activated, a cascade of events occurs. that in combination with all the other cascades result in a given effect.
To really drive home the point: there is no way to predict which receptors in which region of the brain or body are going to be bound to by THC. We haven’t even gotten to the plant and there a gazillion factors that can affect the high.